WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Vascular smooth muscle contraction       ID:04270
C=116; O=7; E=0.06; R=113.15; rawP=2.00e-13; adjP=8.00e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000107796 NA ACTA2 actin, alpha 2, smooth muscle, aorta 59 ENSG00000107796
2  ENSG00000145936 NA KCNMB1 potassium large conductance calcium-activated channel, subfamily M, beta member 1 3779 ENSG00000145936
3  ENSG00000072952 NA MRVI1 murine retrovirus integration site 1 homolog 10335 ENSG00000072952
4  ENSG00000163017 NA ACTG2 actin, gamma 2, smooth muscle, enteric 72 ENSG00000163017
5  ENSG00000065534 NA MYLK myosin light chain kinase 4638 ENSG00000065534
6  ENSG00000156113 NA KCNMA1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 3778 ENSG00000156113
7  ENSG00000133392 NA MYH11 myosin, heavy chain 11, smooth muscle 4629 ENSG00000133392


Database:KEGG pathway       Name:Calcium signaling pathway       ID:04020
C=177; O=2; E=0.09; R=21.19; rawP=0.0040; adjP=0.0057
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000065534 NA MYLK myosin light chain kinase 4638 ENSG00000065534
2  ENSG00000196557 NA CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 8912 ENSG00000196557


Database:KEGG pathway       Name:Regulation of actin cytoskeleton       ID:04810
C=213; O=2; E=0.11; R=17.61; rawP=0.0057; adjP=0.0057
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077943 NA ITGA8 integrin, alpha 8 8516 ENSG00000077943
2  ENSG00000065534 NA MYLK myosin light chain kinase 4638 ENSG00000065534


Database:KEGG pathway       Name:Focal adhesion       ID:04510
C=200; O=2; E=0.11; R=18.75; rawP=0.0051; adjP=0.0057
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077943 NA ITGA8 integrin, alpha 8 8516 ENSG00000077943
2  ENSG00000065534 NA MYLK myosin light chain kinase 4638 ENSG00000065534




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).